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Cease having HEPBEST 25MG TABLET and contact your health practitioner right away if you encounter any of the subsequent Negative effects:
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Cần xem xét ở tất cả bệnh nhân các chỉ số creatinine huyết thanh, photpho huyết thanh, tốc độ thanh thải creatinine, đường nhiệu và protein niệu trước khi bắt đầu sử dụng và trong khi điều trị bằng tenofovir alafenamide 25mg.
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The LD50 of tenofovir alafenamide has not been documented. In conditions of overdose, continuous checking of important symptoms is required since the adverse outcomes in high doses hasn't been evaluated.
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In scientific trials, the described quantity of distribution of tenofovir alafenamide was larger than one hundred L.
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Tenofovir alafenamide is then converted to tenofovir by hydrolysis mainly by carboxylesterase 1 (CES1) in Principal hepatocytes. Intracellular tenofovir is subsequently phosphorylated by mobile kinases for the pharmacologically active metabolite tenofovir diphosphate.